A. Saven – Hairy Cell Leukemia

Hairy cell leukemia (HCL) has assumed a level of great medical importance, despite its relative rarity as a chronic lymphoid leukemia. This is because it is a unique, and peculiar, clinicopathologic entity which demonstrates unparalleled sensitivity to systemic therapy. Accordingly, it has served as a model for rational drug development. Although splenectomy regularly normalizes the disease-associ